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The adaptation of muscles and tendons to use, disuse and pathology is the primary theme of this research program. In particular, we seek to understand the impact of these conditions on locomotion and other functional activities. Our aim is to improve scientific and clinical understanding of tendon and muscle morphology, biomechanics, physiology, and pathology. In the presence of pathology, we relate the biomechanical characteristics to corresponding signs and symptoms, resulting losses of function, and potential for developing disability. Our program fosters multidisciplinary collaborations between scientists and clinicians in basic and clinical studies.
Tendon Biomechanics
Tendinopathy is a significant source of morbidity worldwide. We examine morphological and functional predispositions which may contribute to the development of tendinopathy. Laboratory and clinilcal studies of lower extremity tendons (tibialis posterior, Achilles and patellar) are currently underway. We are interested in identifying mechanisms and predisposing factors of effective or ineffective adaptations, with an emphasis on mechanical stiffness of the musculotendinous unit and its relation to intersegmental dynamics during varying forms of locomotion. The long term goal of our research program is to provide the basis for studies examining efficacy and effectiveness studies of non-surgical and surgical interventions. Ultimately, we hope to provide scientific foundation for the prevention of tendinopathies.
Spine Biomechanics
Low back dysfunction is the main cause of musculoskeletal disability. We have developed a multidisciplinary research program to systematically examine the paraspinal musculature and its response to disuse, pathology and rehabilitative strategies. Our studies of lumbar intervertebral kinematics inform us about how structural morphology dictates motion in the absence or presence of pathology. These findings, coupled with anthropometric and electrophysiological analyses, provide the basis for an optimal framework of lower lumbar spine mechanics. This framework can provide essential information leading to the development of intervention strategies. |